Avengers (1963) #227
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Characters
Earth's Mightiest Heroes joined forces to take on threats that were too big for any one hero to tackle. With a roster that has included Captain America, Iron Man, Ant-Man, Hulk, Thor, Wasp and dozens more over the years, the Avengers have come to be regarded as Earth's No. 1 team.
Seriously wounded, young lawyer Jennifer Walters was given a blood transfusion by her cousin Bruce Banner. Usually in better control of her powers and temper than the Hulk, She-Hulk has been a high profile New York lawyer as well as an upstanding member of both the Avengers and Fantastic Four.
When Janet Van Dyne's father died, she convinced her father's associate Hank Pym to give her a supply of "Pym particles"; Pym also subjected her to a procedure which granted her the ability to, upon shrinking, grow wings and fire blasts of energy, which she called her "wasp's stings."
After brilliant scientist Henry Pym discovered a process in which he could manipulate a newly discovered group of subatomic particles through magnetic fields, he tested the serums on himself and accidentally shrunk himself to the size of an ant.