Dark Avengers (2012) #190
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Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
Shang-Chi is the son of an internationally-renowned and powerful criminal mastermind whose childhood was a lonely one, full of constant training in rigorous mental and martial arts, with only limited contact with his parents.
The Hulk fathered a son while on the planet Sakaar, but thought him killed while still in his mother's womb; he was wrong.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
With the end of the Vietnam War, John Walker thought his dreams of becoming a war hero had also ended, until he learned of the Power Broker, who could give anyone superhuman powers, which Walker used to first become Super-Patriot and later, U.S. Agent.