Dark Avengers (2012) #188
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Abandoned by his mother, Matt Murdock was raised by his father, boxer "Battling Jack" Murdock, in Hell's Kitchen. Realizing that rules were needed to prevent people from behaving badly, young Matt decided to study law; however, when he saved a man from an oncoming truck, it spilled a radioactive cargo that rendered Matt blind while enhancing his remaining senses. Under the harsh tutelage of blind martial arts master Stick, Matt mastered his heightened senses and became a formidable fighter.
Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
Shang-Chi is the son of an internationally-renowned and powerful criminal mastermind whose childhood was a lonely one, full of constant training in rigorous mental and martial arts, with only limited contact with his parents.
The Hulk fathered a son while on the planet Sakaar, but thought him killed while still in his mother's womb; he was wrong.
Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
Although she was able to use the cat's-head amulet to change back to her human form, Greer Nelson became so accustomed to and enamored of her feline form that she seldom made the transformation.