Amazing Spider-Man (1999) #685
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Mary Jane Watson was the guiding light in Peter Parker's life, and their love had overcome countless obstacles.
Ruth Bat-Seraph is an Israeli national who, along with her family, was taken to a special community by the Israeli government when her genetic mutation manifested.
Silver Sable trained her entire life, becoming a master of a wide variety of weapons and training in all forms of hand-to-hand combat in preparation for the day she would inherit leadership of the Wild Pack.
Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.