Amazing Spider-Man (1999) #665
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Characters
Mary Jane Watson was the guiding light in Peter Parker's life, and their love had overcome countless obstacles.
Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
Flash Thompson was the high school bully of Peter Parker while also being one of Spider-Man's biggest fans. After losing his legs during military service, he became the new Venom, working as an operative of the United States government.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.