Amazing Spider-Man (1999) #653
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Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.
Escaping the taunts of her fellow school students regarding her physical mutation, Los-Angeles born Doreen Green fled into the nearby woods where she quickly discovered her affinity for squirrels.