Amazing Spider-Man (1999) #647
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Characters
Mary Jane Watson was the guiding light in Peter Parker's life, and their love had overcome countless obstacles.
Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.
Flash Thompson was the high school bully of Peter Parker while also being one of Spider-Man's biggest fans. After losing his legs during military service, he became the new Venom, working as an operative of the United States government.