Ultimate Comics Mystery (2010) #4
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Characters
Peter’s relatively normal life changed abruptly during a school trip to Osborn Industries, Inc, where the company had been working on a super soldier serum, the Oz Compound; a spider exposed to it escaped and bit Peter before it was destroyed.
When young Jessica Drew suffered uranium poisoning in 1931, her father was forced to inject her with his untested spider serum and seal her in a genetic accelerator.