Ultimate X-Men (2001) #100
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The only daughter of a wealthy diamond miner, Shanna grew up in the Zaire jungles, where, at age six, she witnessed her father’s accidental fatal shooting of her mother, starting a lifelong loathing of firearms.
Ororo Munroe was raised in Morocco, learning English from American films, and after her family was murdered she fled to America, stealing cars in Harlem before relocating to Texas.
William Stryker became convinced that Satan had a plot to corrupt humankind by taking over their souls while still in the womb, resulting in their mutations.
Decades after participating in military airdrops with Captain America during WWII, James Howlett was abducted and experimented upon by a covert government unit, who bonded unbreakable adamantium to his skeleton, implanted three claws in each arm, dubbed him Weapon X and supposedly programmed him to kill any human he came into contact with.