Doctor Strange, Sorcerer Supreme (1988) #41
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Caught in a gamma bomb explosion while trying to save the life of a teenager, Dr. Bruce Banner was transformed into the incredibly powerful creature called the Hulk. An all too often misunderstood hero, the angrier the Hulk gets, the stronger the Hulk gets.
When Zenn-La was threatened by the world-devouring entity known as Galactus, Norrin Radd stood up for his home planet and offered to work for Galactus, finding him new planets to eat, in exchange for saving his own. Years later, the Surfer has protected Earth and many other planets, becoming one of the greatest heroes in the universe.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.