Marvel Two-in-One (1974) #61
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Adam Warlock is an artificially created human who was born in a cocoon at a scientific complex called The Beehive.
Caught in a gamma bomb explosion while trying to save the life of a teenager, Dr. Bruce Banner was transformed into the incredibly powerful creature called the Hulk. An all too often misunderstood hero, the angrier the Hulk gets, the stronger the Hulk gets.
Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
Bitten by a radioactive spider, high school student Peter Parker gained the speed, strength and powers of a spider. Adopting the name Spider-Man, Peter hoped to start a career using his new abilities. Taught that with great power comes great responsibility, Spidey has vowed to use his powers to help people.
The Mad Titan Thanos, a melancholy, brooding individual, consumed with the concept of death, sought out personal power and increased strength, endowing himself with cybernetic implants until he became more powerful than any of his brethren.