Wolverine/Doop (2003) #1
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Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.
The Collector (Taneleer Tivan)
The Collector is one of the oldest living beings in the universe, having been among the first of the universe's races to become sentient in the wake of the Big Bang.