Iron Man (1996) #3
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Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
After the apparent death of Baron von Strucker, Viper took the name Madame Hydra and took control of the New York-based faction of Hydra.