Wolverine (1988) #173
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Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
Dr. Michael Twoyoungmen was a surgeon who found that modern science was insufficient to accomplish everything he wished to do, and so he turned to mysticism that his grandfather told him about.
Narya's origins trace back to ancient times when the Eskimo Gods of the North battled the mystical Great Beasts for the fate of the world.
Edward Whelan was found roaming the streets of New York by Baron Helmut Zemo, who subjected Whelan to Zemo's genetic experiments, which granted him superhuman strength, but, in the process of the mutation, he manifested a rat-like physical appearance, and was called Vermin.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.