Uncanny X-Men (1981) #272
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Seriously wounded, young lawyer Jennifer Walters was given a blood transfusion by her cousin Bruce Banner. Usually in better control of her powers and temper than the Hulk, She-Hulk has been a high profile New York lawyer as well as an upstanding member of both the Avengers and Fantastic Four.
Ororo Monroe is the descendant of an ancient line of African priestesses, all of whom have white hair, blue eyes, and the potential to wield magic.
Growing up in a wealthy Brazilian family, Roberto da Costa was forging a career as a skilled soccer player until his mutant nature manifested during a match.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.