Uncanny X-Men (1981) #257
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One of the oldest and more powerful mutants ever, Amahl Farouk has been a threat to mankind at least for decades. He was the first evil mutant met by Charles Xavier, convincing him of the need of the X-Men.
Ororo Monroe is the descendant of an ancient line of African priestesses, all of whom have white hair, blue eyes, and the potential to wield magic.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.