Uncanny X-Men (1981) #222
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Vertigo was a native of the Savage Land and mutated by the mutant known as Magneto, granting her the power to alter the perceptions of others.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.