Uncanny X-Men (1981) #213
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Adam Warlock is an artificially created human who was born in a cocoon at a scientific complex called The Beehive.
Ororo Monroe is the descendant of an ancient line of African priestesses, all of whom have white hair, blue eyes, and the potential to wield magic.
Growing up in a wealthy Brazilian family, Roberto da Costa was forging a career as a skilled soccer player until his mutant nature manifested during a match.
Vertigo was a native of the Savage Land and mutated by the mutant known as Magneto, granting her the power to alter the perceptions of others.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.