Uncanny X-Men (1981) #172
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Ororo Monroe is the descendant of an ancient line of African priestesses, all of whom have white hair, blue eyes, and the potential to wield magic.
After the apparent death of Baron von Strucker, Viper took the name Madame Hydra and took control of the New York-based faction of Hydra.
Born with super-human senses and the power to heal from almost any wound, Wolverine was captured by a secret Canadian organization and given an unbreakable skeleton and claws. Treated like an animal, it took years for him to control himself. Now, he's a premiere member of both the X-Men and the Avengers.