Universe X (2000) #9
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Abandoned by his mother, Matt Murdock was raised by his father, boxer "Battling Jack" Murdock, in Hell's Kitchen. Realizing that rules were needed to prevent people from behaving badly, young Matt decided to study law; however, when he saved a man from an oncoming truck, it spilled a radioactive cargo that rendered Matt blind while enhancing his remaining senses. Under the harsh tutelage of blind martial arts master Stick, Matt mastered his heightened senses and became a formidable fighter.
Shiro Yoshida’s mother was exposed to the atomic devastation of Hiroshima during World War II and died giving birth to him.
The Supreme Intelligence is an organic, computer construct, created by the Kree to act as their supreme leader.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
As the Norse God of thunder and lightning, Thor wields one of the greatest weapons ever made, the enchanted hammer Mjolnir. While others have described Thor as an over-muscled, oafish imbecile, he's quite smart and compassionate. He's self-assured, and he would never, ever stop fighting for a worthwhile cause.