Universe X (2000) #7
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Wounded, captured and forced to build a weapon by his enemies, billionaire industrialist Tony Stark instead created an advanced suit of armor to save his life and escape captivity. Now with a new outlook on life, Tony uses his money and intelligence to make the world a safer, better place as Iron Man.
When Zenn-La was threatened by the world-devouring entity known as Galactus, Norrin Radd stood up for his home planet and offered to work for Galactus, finding him new planets to eat, in exchange for saving his own. Years later, the Surfer has protected Earth and many other planets, becoming one of the greatest heroes in the universe.
The Supreme Intelligence is an organic, computer construct, created by the Kree to act as their supreme leader.
The Mad Titan Thanos, a melancholy, brooding individual, consumed with the concept of death, sought out personal power and increased strength, endowing himself with cybernetic implants until he became more powerful than any of his brethren.
The radiation that mutated Reed Richards, Sue Storm and Johnny Storm into superhuman beings had also mutated Ben Grimm, transforming him into a grotesque, rock-hided strongman dubbed the Thing.
As the Norse God of thunder and lightning, Thor wields one of the greatest weapons ever made, the enchanted hammer Mjolnir. While others have described Thor as an over-muscled, oafish imbecile, he's quite smart and compassionate. He's self-assured, and he would never, ever stop fighting for a worthwhile cause.